Can diuretics cause cancer?

Does hydrochlorothiazide cause cancer?

Hydrochlorothiazide is photosensitizing and has been linked to lip cancer. We found a dose-dependent increased risk of nonmelanoma skin cancer, particularly squamous cell carcinoma, among users of hydrochlorothiazide.

What are complications of diuretics?

The more common side effects of diuretics include:

  • too little potassium in the blood.
  • too much potassium in the blood (for potassium-sparing diuretics)
  • low sodium levels.
  • headache.
  • dizziness.
  • thirst.
  • increased blood sugar.
  • muscle cramps.

Can hydrochlorothiazide cause kidney cancer?

Conclusions: In a single-center cohort of kidney, combined kidney-pancreas, and pancreas transplant recipients, exposure to hydrochlorothiazide was associated with a two-fold higher risk of squamous cell carcinoma and no higher risk of basal cell carcinoma.

Do all diuretics cause skin cancer?

Diuretic use is associated with the development of skin cancers including malignant melanoma, basal cell carcinoma, and squamous cell carcinoma, ranging from 20% increase in risk to nearly 3 times the risk compared with nonusers (SOR: B, consistent cohort studies).

Is there a black box warning for hydrochlorothiazide?

A black box warning is attached to hydrochlorothiazide due to its ability to cause fetal mortality in women using the drug to treat high blood pressure.

Can diuretics cause permanent damage?

Loop agents and thiazides may lead to hyponatremia, which, in the case of thiazides, may cause permanent neurologic damage. Dose-related reversible or irreversible ototoxicity may complicate treatment with loop agents.

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What is the safest diuretic?

TUESDAY, Feb. 18, 2020 (HealthDay News) — Patients taking a common diuretic to help lower blood pressure may be better off with a similarly effective but safer one, a new study suggests. Current guidelines recommend the drug chlorthalidone (Thalitone) as the first-line diuretic.

Are diuretics bad for kidneys?

Diuretics. Doctors use these medicines, also known as water pills, to treat high blood pressure and some kinds of swelling. They help your body get rid of extra fluid. But they can sometimes dehydrate you, which can be bad for your kidneys.

Who should not take hydrochlorothiazide?

You should not use hydrochlorothiazide if you are unable to urinate. Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.

Can you just stop taking hydrochlorothiazide?

Do not stop using hydrochlorothiazide and metoprolol suddenly, even if you feel fine. Stopping suddenly may cause serious or life-threatening heart problems. Follow your doctor’s instructions about tapering your dose.