Can viral hepatitis cause hepatocellular carcinoma?

Which virus can causes the hepatocellular carcinoma?

Hepatocellular carcinoma (HCC) is the most common form of liver cancer; most cases of HCC (approximately 80%) are associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections.

Can viral hepatitis cause liver cancer?

Chronic viral hepatitis

Worldwide, the most common risk factor for liver cancer is chronic (long-term) infection with hepatitis B virus (HBV) or hepatitis C virus (HCV). These infections lead to cirrhosis of the liver and are responsible for making liver cancer the most common cancer in many parts of the world.

What is the most common cause of hepatocellular carcinoma?

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. Hepatocellular carcinoma occurs most often in people with chronic liver diseases, such as cirrhosis caused by hepatitis B or hepatitis C infection.

Which of these hepatitis viruses cause hepatocellular carcinoma of the liver?

Hepatitis B virus (HBV) is one of the most common chronic infections worldwide, with an estimated 257 million chronically infected subjects, and the leading cause for hepatocellular carcinoma (HCC) worldwide [1].

How does hepatocellular carcinoma develop?

This serious disease happens when liver cells are damaged and replaced with scar tissue. Many things can cause it: hepatitis B or C infection, alcohol drinking, certain drugs, and too much iron stored in the liver.

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What viruses can cause cancer?

Epstein-Barr virus, human papilloma virus, hepatitis B virus, and human herpes virus-8 are the four DNA viruses that are capable of causing the development of human cancers. Human T lymphotrophic virus type 1 and hepatitis C viruses are the two RNA viruses that contribute to human cancers.

What cancer is caused by Epstein Barr virus?

EBV infection increases a person’s risk of getting nasopharyngeal cancer (cancer of the area in the back of the nose) and certain types of fast-growing lymphomas such as Burkitt lymphoma. It may also be linked to Hodgkin lymphoma and some cases of stomach cancer.

What is the life expectancy of a person with hepatocellular carcinoma?

Unfortunately, HCC is typically diagnosed late in its course, with a median survival following diagnosis of approximately 6 to 20 months. In the United States, 2 years survival is less than 50% and 5-year survival is only 10%.

How long can you live with hepatocellular carcinoma?

Average follow-up for all HCC patients in this study was 20.4 months. Overall median survival of all 389 patients was 11 months from the date of diagnosis.

Can you survive hepatocellular carcinoma?

Overall prognosis for survival is poor, with a 5-year relative survival rate of 18.4%. By stage, the relative 5-year survival is 32.6% in patients diagnosed with localized disease, 10.8% with regional disease, and 2.4% with distant disease.