Is Femara a cancer drug?

Is letrozole a cancer drug?

About letrozole

Letrozole is a medicine used for treating breast cancer. It can also help prevent breast cancer coming back. It is mainly prescribed for women who have been through the menopause and have a type of cancer called “hormone-dependent” breast cancer.

What type of drug is Femara?

Drug Type:

Femara is a hormone therapy. Femara is classified as an aromatase inhibitor.

Why was letrozole banned?

That study also found no significant difference in the rate of overall abnormalities, but found that congenital cardiac anomalies was significantly higher in the clomiphene group compared to the letrozole group. Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.

Is letrozole chemotherapy or hormone therapy?

Letrozole is a hormone therapy. Letrozole is classified as an aromatase inhibitor. (For more detail, see “How Letrozole Works” section below).

How effective is letrozole for cancer?

In the BIG 1-98 trial, 73.8% of women who received letrozole alone had a disease-free survival at 8 years, compared to 70.4% of women who received tamoxifen alone.

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Why is letrozole considered chemotherapy?

Traditional chemotherapy agents stop cancer cells from growing, dividing, and making more cells. Letrozole works by blocking the action of the enzyme aromatase, which prevents the body from converting androgens into estrogens.

Is Femara considered chemotherapy?

Oral chemotherapy is chemotherapy that a person can take by mouth. Some examples of oral chemotherapy medications include: Femara (letrozole) Odomzo (sonidegib)

What does Femara do to your body?

More specifically, Femara is a type of hormone therapy called an aromatase inhibitor. It works by stopping an enzyme (type of protein) called aromatase from working as usual. This enzyme is the main way that your body makes estrogen after you’ve gone through menopause.

How long can you take Femara?

In most cases, you’ll take Femara for 5 years. Doctors may recommend that some women take it for a longer period of time.

What is the success rate of letrozole?

In the intention-to-treat analysis, women who received letrozole alone had a disease-free survival rate of 73.8 percent at 8 years, compared with a rate of 70.4 percent for women who received tamoxifen alone.

Can letrozole cause kidney problems?

It can be a common cause of acute kidney injury, traditional chemotherapy agents have been associated with various forms of renal damage, but this is not commonly seen with anti-hormone therapy. Here we report a case of aromatase inhibitor associated acute interstitial nephritis with the use of letrozole.

Can I take vitamin D with letrozole?

No interactions were found between letrozole and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

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What vitamins should I take with letrozole?

Patients who received letrozole for a longer duration had a low concentration of serum 25 (OH) vitamin D. Vitamin D3 and calcium supplementation increased the concentrations of calcium, phosphorous and decreased the concentrations of parathyroid hormone and alkaline phosphatase.

What are the worst side effects of letrozole?

Side effects of letrozole (Femara)

  • aching or pain in the joints or muscles.
  • menopausal symptoms.
  • low mood and depression.
  • difficulty sleeping.
  • fatigue.
  • osteoporosis.
  • high blood pressure and cholesterol.