What is a germ cell tumor?
Germ cell tumors are growths of cells that form from reproductive cells. The tumors may be cancerous or not cancerous. Most germ cell tumors occur in the testicles or the ovaries.
What is the most common germ cell tumor?
Teratomas are the most common type of germ cell tumor to develop in extragonadal (not in the ovary or testes) areas. Doctors usually treat teratomas with surgery because chemotherapy doesn’t work in a benign tumor.
What is granulosa cell Tumour?
Granulosa cell tumours are tumours that arise from granulosa cells. They are estrogen secreting tumors and present as large, complex, ovarian masses. These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours.
Are granulosa cell tumors malignant?
Ovarian granulosa cell tumor (GCT) is a malignant tumor with slow progression. The recurrence of granulosa cell tumor often happens after 5 years, leading to a ‘forgotten tumor’ by the patient.
Which tumors are considered germ cell tumors?
The most common types of germ cell tumors include:
- Teratomas. Teratomas contain cells from the three germ layers: ectoderm, mesoderm, and endoderm. …
- Germinomas. Germinomas are malignant germ cell tumors. …
- Endodermal sinus tumor or yolk sac tumors. …
- Choriocarcinoma. …
- Embryonal carcinoma.
What are the two types of germ cell tumors?
There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.
What is germ cell?
Listen to pronunciation. (jerm sel) A reproductive cell of the body. Germ cells are egg cells in females and sperm cells in males.
Are granulosa cell tumors benign?
GCTs are thought to be tumors of low malignant potential. Most of these tumors follow a benign course, with only a small percentage showing aggressive behavior, perhaps due to early stage at diagnosis. Metastatic disease can involve any organ system, although tumor growth usually is confined to the abdomen and pelvis.
Do granulosa cell tumors produce estrogen?
Adult granulosa cell tumors are common among women in their fifties and are known for estrogen production, although about 30% of cases do not produce estradiol . The major symptom of granulosa cell tumors is postmenopausal genital bleeding, which is attributed to estrogen production .