What does in situ mean in medical terms?
(in SY-too) In its original place. For example, in carcinoma in situ, abnormal cells are found only in the place where they first formed.
Is carcinoma in situ curable?
Stage 1 to stage 4 are all considered “invasive” cancers, as they have spread beyond something called the “basement” membrane in tissues. When cancers are found at this stage, they should theoretically be 100 percent curable.
Is carcinoma in situ reversible?
Precancer progresses through dysplastic phases to carcinoma in situ and these changes can be documented by aneuploidy in the abnormal cells. Some of all these degrees of dysplasia, including carcinoma in situ, have been shown to be reversible.
What stage is carcinoma in situ?
In general, carcinoma in situ is the earliest form of cancer, and is considered stage 0. An example of carcinoma in situ is ductal carcinoma in situ, or DCIS, which is considered an early form of breast cancer and occurs when abnormal cells form a breast’s milk duct.
What is the treatment for carcinoma in situ?
Treatment of DCIS has a high likelihood of success, in most instances removing the tumor and preventing any recurrence. In most people, treatment options for DCIS include: Breast-conserving surgery (lumpectomy) and radiation therapy. Breast-removing surgery (mastectomy)
What causes carcinoma in situ?
It’s not clear what causes DCIS. DCIS forms when genetic mutations occur in the DNA of breast duct cells. The genetic mutations cause the cells to appear abnormal, but the cells don’t yet have the ability to break out of the breast duct.
What are the symptoms of carcinoma in situ?
When ductal carcinoma in situ does produce symptoms, the most common include:
- Breast pain.
- Bloody discharge from the nipple.
- A palpable lump in the breast tissue.
- A red, scaly rash known as Paget’s disease of the breast.