Can raloxifene cause uterine cancer?
Raloxifene does not act like estrogen in the uterus and is not linked to an increased risk of uterine cancer. Although tamoxifen does increase the risk of uterine cancer, the overall increase in risk is low (less than 1%).
Does raloxifene increase risk of ovarian cancer?
The relative risk of ovarian cancer associated with raloxifene therapy was 0.50 (95% confidence interval, 0.19-1.35). Conclusion: Raloxifene use was not associated with an increased risk for ovarian cancer.
Which is safer tamoxifen or raloxifene?
This means that raloxifene reduces risk of non-invasive breast cancer by about 38 percent compared to tamoxifen reducing risk for this type of cancer by about 50 percent; or raloxifene is about 78 percent as effective as tamoxifen in reducing the risk of noninvasive breast cancer over almost 7 years.
What are the side effects of Evista?
103 The most common side effects of EVISTA are hot flashes, leg cramps, swelling of the feet, 104 ankles, and legs, flu syndrome, joint pain, and sweating. Hot flashes are more common during 105 the first 6 months after starting treatment.
How long should you take Evista for osteoporosis?
In the STAR trial, women took Evista for 5 years. Depending on your unique situation, your doctor may recommend that you take Evista for a longer or shorter amount of time.
What is the 5 year pill for breast cancer?
Tamoxifen. Tamoxifen is usually taken daily in pill form. It’s often used to reduce the risk of cancer recurrence in women who have been treated for early-stage breast cancer. In this situation, it’s typically taken for five to 10 years.
Can I just stop taking raloxifene?
Do not take more or less of it or take it more often than prescribed by your doctor. Continue to take raloxifene even if you feel well. Do not stop taking raloxifene without talking to your doctor.
What are contraindications of raloxifene?
Contraindications to raloxifene include past medical history of deep venous thrombosis, renal vein thrombosis, pulmonary embolism, malignancy, active smoking, or any thrombophilia (factor V Leiden deficiency, prothrombin gene mutation G20210A, antiphospholipid syndrome, deficiency of antithrombin, protein c and s …
Is Evista considered HRT?
4. Bottom Line. Evista is not a hormone but it mimics estrogen, and may be used to treat osteoporosis in postmenopausal women or to lower the risk of invasive breast cancer in women with osteoporosis.
Does raloxifene weaken your immune system?
These data suggest that raloxifene and tamoxifen may decrease the strength of immune responses in vivo through modulation of DC differentiation and activation.