Does having chemo as a child affect fertility?

Does childhood chemo cause infertility?

Infertility remains one of the most common and life-altering complications experienced by adults treated for cancer during childhood. Surgery, radiation, or chemotherapy that negatively affects any component of the hypothalamic-pituitary-gonadal axis may compromise reproductive outcomes in childhood cancer survivors.

What are the chances of being infertile after chemotherapy?

Some women who have normal periods after chemotherapy may be able to get pregnant with no difficulty while others may have trouble getting pregnant. This is because chemotherapy can damage the immature eggs in the ovaries. When your periods return after chemotherapy, it means that some eggs are maturing.

Can childhood leukemia survivors get pregnant?

“We have known for some time, from data from the Childhood Cancer Survivor Study,2 that the risk of ever becoming pregnant is decreased for female childhood cancer survivors. The relative risk is 0.8,” Dr. Mulrooney reported. “It is reduced similarly for male childhood cancer survivors, a relative risk of 0.6.”

How does chemotherapy affect the reproductive system?

Chemotherapy (especially alkylating agents) can affect the ovaries, causing them to stop releasing eggs and estrogen. This is called primary ovarian insufficiency (POI). Sometimes POI is temporary and your menstrual periods and fertility return after treatment.

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Does chemo affect egg quality?

Chemotherapy (chemo) can damage the eggs that are in your ovaries. You’re born with all the eggs you will ever have. Some chemo medicines are more likely to cause infertility than others.

Which chemotherapy causes infertility?

Chemo drugs that are linked to the risk of infertility in females are:

  • Busulfan.
  • Carboplatin.
  • Carmustine.
  • Chlorambucil.
  • Cisplatin.
  • Cyclophosphamide.
  • Cytosine arabinoside.
  • Doxorubicin.

Does chemo affect menstrual cycle?

Some chemotherapy drugs can damage the ovaries and stop regular menstrual cycles (amenorrhea). In women under 40, it’s often temporary and periods start again [31]. In women over 40, it’s more often permanent (early menopause) [31].

Can fertility come back after chemo?

If chemotherapy has made you infertile, it can be difficult to tell whether this is permanent or not. Some men stay infertile but others find their sperm returns to normal and their fertility comes back. It can take a few months or sometimes years for fertility to return to normal.

Does chemotherapy for leukemia make you sterile?

Chemotherapy and radiation can cause side effects as well as long-term and late effects, which can appear months or years after treatment. One possible late effect is infertility, the inability to conceive a child naturally.