Frequent question: WHO odontogenic tumors definition?

WHO classification odontogenic Tumours?

The next edition of the WHO’s classification of odontogenic cysts, tumors and maxillofacial bone tumors was published in early 2017 (Table 1).

Table 2.

Class of lesions Tumour Genetic alteration
Odontogenic carcinomas Ameloblastic carcinoma BRAF
Clear cell odontogenic carcinoma EWSR1, ATF1

Who Adenomatoid odontogenic tumor?

Adenomatoid odontogenic tumor (AOT) is a rare tumor of epithelial origin comprising 3% of all the odontogenic tumors. It is a benign, painless, noninvasive, and slow-growing lesion, with a relative frequency of 2.2-13% and often misdiagnosed as an odontogenic cyst on clinical examination.

How does odontogenic tumors develop?

Odontogenic lesions arise from tissue within the jaws that has the capability of differentiating into the tissue elements found in teeth or periodontal membrane. Therefore they are found most commonly in the tooth bearing regions of the jaws.

What does odontogenic mean?

Medical Definition of odontogenic

1 : forming or capable of forming teeth odontogenic tissues. 2 : containing or arising from odontogenic tissues odontogenic tumors.

What is a CEOT?

A calcifying epithelial odontogenic tumor (CEOT) is a locally invasive epithelial neoplasm characterized by the development of intraepithelial structures, probably of an amyloid-like nature, which may become calcified and liberated as the cells break down.

Who odontogenic tumor classification 2005?

Type 1: simple cystic. Type 2: CCOT associated with an odontoma. Type 3: with ameloblastomatous-like proliferation. Type 4: associated with other benign odontogenic tumors other than odontoma.

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What causes odontogenic cysts?

Periapical Cyst (Odontogenic Cyst Or Radicular Cyst)

The death or necrosis of the pulp tissue inside the tooth, which stems from tooth decay or trauma will cause this type of cyst. The process of pulpal necrosis causes inflammation and the release of toxins at the apex or end of the root tip.

What is odontogenic cyst?

Odontogenic cysts are epithelial-lined pathologic cavities and surrounded by fibrous connective tissue that originate from odontogenic tissues that occur in tooth-bearing regions of maxilla and mandible. Cystic conditions of the jaw cause bony destruction and may cause resorption or displacement of adjacent teeth.

How can you tell the difference between AOT and Dentigerous cysts?

The characteristic radiographic difference between dentigerous cyst and follicular AOT is that the radiolucency in the former is never associated with part of the root (always attached at the cervix) whereas in the latter it is most commonly associated with the part of the root.

What is an odontogenic fibroma?

Central odontogenic fibroma (COF) is an extremely rare benign tumor that accounts for 0.1% of all odontogenic tumors. It appears as an asymptomatic expansion of the cortical plate of the mandible or maxilla. Radiologically it presents as a unilocular or multilocular radiolucency.