How rare is melanoma of the eye?

What are the chances of getting ocular melanoma?

The uvea contains melanocytes. Uveal melanoma is another name for ocular melanoma. This is the most common form of eye cancer in adults, but it’s still rare. Your odds of getting it are about 6 in 1 million.

How fatal is ocular melanoma?

The 5-year survival rate for eye melanoma is 82%. When melanoma does not spread outside the eye, the 5-year relative survival rate is about 85%. The 5-year survival rate for those with disease that has spread to surrounding tissues or organs and/or the regional lymph nodes is 71%.

How aggressive is ocular melanoma?

This is an aggressive type of cancer that can potentially spread to other areas of the body, most often to the liver. Immediate treatment is often necessary. The approach depends on the size and placement of the tumor, and the stage at which it is found. The two most common treatments are radiation therapy and surgery.

How long does eye melanoma take to develop?

There is no known cause, though incidence is highest among people with lighter skin and blue eyes. Approximately 50% of patients with OM will develop metastases by 10 to 15 years after diagnosis (a small percentage of people will develop metastases even later i.e. 20-25 years after their initial diagnosis).

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Where does melanoma of the eye spread to?

The liver is the most common site of metastasis in ocular melanoma. Among those who develop metastatic disease, 90% of patients develop liver disease. However, ocular melanoma can spread to any organ in the body. After the liver, common sites include the lung, bones and brain.

Can ocular melanoma come back?

Most uveal melanomas are still only within the eye when they are first diagnosed. It is rare for the cancer to have already spread outside of the eye. But unfortunately, in about half of all patients the melanoma will come back at some point after treatment. Cancer that comes back after treatment is called recurrent.

Can eye melanoma spread to the brain?

Metastasis of the ocular malignant melanoma to the brain is extremely rare and most often occurs simultaneously with liver metastases. Lorigan et al., in clinical and radiological studies, found a total of five cases of brain metastases in 110 cases of metastatic choroidal melanoma [3].

How long does it take melanoma to metastasis?

214 patients with MM were evaluated retrospectively. Distant metastases (82%) were the most frequent for patients initially metastatic. The median and 1-year survival rates of initially MM patients were 10 months and 41%, respectively. The median time to metastasis for patients with localized disease was 28 months.