Is Basal cell skin cancer aggressive?

How aggressive is basal cell?

BCC generally has a clinical course characterized by slow growth, minimal soft tissue invasiveness, and a high response rate to conventional therapies. Occasionally, however, BCC behaves aggressively, with deep invasion, recurrence, and potential regional and distant metastasis.

What does aggressive BCC look like?

What does BCC look like? BCCs can look like open sores, red patches, pink growths, shiny bumps, scars or growths with slightly elevated, rolled edges and/or a central indentation. At times, BCCs may ooze, crust, itch or bleed. The lesions commonly arise in sun-exposed areas of the body.

How long does it take for basal cell carcinoma to spread?

The tumors enlarge very slowly, sometimes so slowly that they go unnoticed as new growths. However, the growth rate varies greatly from tumor to tumor, with some growing as much as ½ inch (about 1 centimeter) in a year.

What is an aggressive BCC?

Aggressive BCC tends to have no or less pink within the tumor area and absent or few vessels in the central tumor area compared to other BCC subtypes. Superficial BCC typically has the dermatoscopy vascular features of increased pink and relative absence of large diameter vessels.

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What is the survival rate for basal cell carcinoma?

The prognosis for patients with BCC is excellent, with a 100% survival rate for cases that have not spread to other sites. Nevertheless, if BCC is allowed to progress, it can result in significant morbidity, and cosmetic disfigurement is not uncommon.

Do you get pain with basal cell carcinoma?

It may feel itchy, tender, or painful. Basal cell and squamous cell skin cancers can look like a variety of marks on the skin. The key warning signs are a new growth, a spot or bump that’s getting larger over time, or a sore that doesn’t heal within a few weeks.

Is basal cell carcinoma fatal?

Although basal cell carcinoma grows slowly and doesn’t usually spread to surrounding areas, it can be life-threatening if left untreated.

What is the most aggressive subtype of basal cell carcinoma?

Basosquamous: Also known as metatypical BCC. Under the microscope, this subtype shows cellular features of both basal cell carcinoma and squamous cell carcinoma skin cancer. They are considered a more aggressive variant of BCC.

Does basal cell carcinoma metastasize?

Basal cell carcinoma (BCC) accounts for 80% of all nonmelanoma skin cancers. Its metastasis is extremely rare, ranging between 0.0028 and 0.55 of all BCC cases. The usual metastasis to lymph nodes, lungs, bones, or skin is from the primary tumor situated in the head and neck region in nearly 85% cases.

What is considered a large BCC?

A size larger than 3 cm has been described as a high-risk feature [13]. Notwithstanding the foregoing, this risk factor has been more accurately defined as 1 cm for head and neck tumors and more than 2 cm in other body areas [11].

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What is the average size of a basal cell carcinoma?

Santiago et al. researched 306 cases of BCC with an average size of 5.7 mm (range: 5-6 mm). Excision of the tumors using 2, 3, and 4 mm margins achieved complete excision of the lesion, including the subclinical extension area, in 73.9%, 94.4%, and 99% of cases, respectively.

What happens if you don’t remove basal cell carcinoma?

Without treatment, a basal cell carcinoma could grow — slowly — to encompass a large area of skin on your body. In addition, basal cell carcinoma has the potential to cause ulcers and permanently damage the skin and surrounding tissues.