Which chemo drugs are platinum based?

Which chemo drugs contain platinum?

Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin, and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or acquired resistance severely limit the clinical application of platinum-based treatment.

What is a platinum chemotherapy?

Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer.

Is there platinum in chemotherapy?

Platinum compounds, including cisplatin, carboplatin, and oxaliplatin, are some of the most commonly used and active chemotherapy drugs utilized by oncologists today.

Is Taxol platinum-based?

Usually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol®) or docetaxel (Taxotere®). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks.

Does carboplatin contain platinum?

Platinum-based drugs, such as cisplatin, (trade name Platinol) and carboplatin (trade name Paraplatin) have the chemical element platinum as part of their molecular structure.

Is carboplatin a platinum-based chemo?

The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events).

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Is gemcitabine platinum-based?

Platinum based gemcitabine was widely used in the late 1990s and 2000s as a part of phase studies in MPM because of the synergy between gemcitabine and platinum compounds [4–11]. In those studies, 9.6 to 13 months of overall survival time and 12 % to 48 % of the response rates were reported [4–11].

What does platinum do to the body?

Platinum metal is biologically inert, whereas soluble platinum compounds (e.g., halogenated salts) encountered in occupational settings can cause platinum salt hypersensitivity with symptoms that include bronchitis and asthma after inhalational exposure and contact dermatitis after skin exposure.

What is the difference between carboplatin and cisplatin?

Cisplatin and carboplatin have different toxicity profiles; cisplatin is associated with a higher rate of nausea, vomiting, nephrotoxicity, ototoxicity, while carboplatin has a higher risk of myelosupresssion and neurotoxicity6.

What is platinum material?

Platinum is a dense, malleable, ductile, precious, gray-white transition metal with an atomic number of 78. As a member of group 10 of the periodic table, platinum exhibits excellent corrosion resistance at elevated temperatures. It is sometimes alloyed with iridium to form platiniridium.